Laboratory of Osteoarticular Biology, Bioengineering and Bioimaging UMR CNRS 7052 INSERM U1271

The laboratory of Osteoarticular Biology, Bioengineering and Bioimaging  (B3OA) UMR CNRS 7052 INSERM U1271 is affiliated with the CNRS Department of Science for Engineers , with the INSERM , with the Paris University   and with the Ecole Nationale Vétérinaire de Maisons-Alfort .

Since its creation in 1977, the B3OA has developed a renowned expertise for repair and imaging of osteoarticular tissues. Based on its experience, the mission of the B3O lab is to provide world-class research and education on osteo-articular bioengineering and imaging.

The B3OA lab's important knowledge and unique expertise in tissue engineering, medical imaging and cellular and molecular biology enables it to develop innovative, multidisciplinary approaches for orthopedics, dentistry and radiology.

Our latest news

New lab member: Agathe BEDOUX

Agathe BEDOUX is a M1 student from UTC. Her master project will determine the response of MSCs from patients with osteogenesis imperfecta to shear stress.

New lab member: Nicolas PHILLIPS

Nicolas PHILLIPS is a M1 student at UTC. His master project focuses on the development and evaluation of spectral CT methods for the early detection of osteoarthritis.

New lab member: Karla MIRALLES DOS SANTOS

Karla MIRALLES DOS SANTOS is a M2 student from Ecole Nationale Supérieure des Mines de Saint-Etienne. Her master project will analyse the cellular behavior of MSCs at the contact of…

APINNOV – Nomination for the Promising Patent Trophy

Our patent "Non invasive process for the evaluation of the quality of internal dense connective tissues" has been nominated by APINNOV for their Promising Patent trophy.

New lab member: Etienne GUIGONNAT

Etienne GUIGONNAT is a CNRS development engineer. He is our new administrative and financial manager. He joined our lab on June 2020. See his profile

Our latest publications

Does physical exercise always improve bone quality in rats?

This literature review presents for the first time the effects on five exercise models (treadmill running, wheel running, swimming, resistance training and vibration modes) in three different experimental rat groups (males, females, osteopenic) on bone quality.

Does eccentric-concentric resistance training improve early functional outcomes compared to concentric resistance training after total knee arthroplasty?

This study showed that early combined eccentric-concentric rehabilitation after total knee arthroplasty appears to be associated with improved outcomes compared to classic concentric rehabilitation protocols, on both physical function and quality of life.

Osteogenic-differentiated mesenchymal stem cell-secreted extracellular matrix as a bone morphogenetic protein-2 delivery system for ectopic bone formation

This study provided evidence that the osteoinductive potential of BMP-2 was greater when loaded within an osteogenic MSC-derived ECM.

Impact of astaxanthin on diabetes pathogenesis and chronic complications

In the present review, we aimed to identify the up-to-date biological effects and underlying mechanisms of astaxanthin on the ROS-induced diabetes mellitus-associated metabolic disorders and subsequent complications

Custom-made macroporous bioceramic implants based on triply-periodic minimal surfaces for bone defects in load-bearing sites

This study showed, for the first time, that custom-made TPMS-based bioceramic implants could be produced and successfully implanted in load-bearing sites