Laboratory of Osteoarticular Biology, Bioengineering and Bioimaging UMR CNRS 7052 INSERM U1271

The laboratory of Osteoarticular Biology, Bioengineering and Bioimaging  (B3OA) UMR CNRS 7052 INSERM U1271 is affiliated with the CNRS Department of Science for Engineers , with the INSERM , with the Paris Cité University   and with the Ecole Nationale Vétérinaire de Maisons-Alfort .

Since its creation in 1977, the B3OA has developed a renowned expertise for repair and imaging of osteoarticular tissues. Based on its experience, the mission of the B3O lab is to provide world-class research and education on osteo-articular bioengineering and imaging.

The B3OA lab's important knowledge and unique expertise in tissue engineering, medical imaging and cellular and molecular biology enables it to develop innovative, multidisciplinary approaches for orthopedics, dentistry and radiology.

Our latest news

New lab member: Xavier VESTRIS

Xavier VESTRIS is a Master M2 student from the Orléans University, who joined the B3OA in February 2022.

New lab member: Léa ROUQUIER

Léa ROUQUIER is a PhD candidate at the B3OA since January 2022, in the research theme "Biomedical innovations in orthopaedics: a biophysical approach"

New lab member: Caroline CARON

Caroline CARON is a Master M2 student from the Orléans University, who joined the B3OA in January 2022.

New lab member: Hasan GHANEM

Hasan GHANEM is a Master M2 student from the University of Sorbonne Paris Nord who joined the B3OA in January 2022.

New lab member: Emeline RASCUSSERY

Emeline RASCUSSERY is a M1 student from the University of Cergy-Pontoise who joined the B3OA in January 2022.

New lab member: Axelle GUEDON

Axelle GUEDON is a M2 master student from Université Paris Est Créteil who joined the B3OA in January 2022.

New lab member: Jordan COHEN

Jordan COHEN is a CNRS development engineer(fixed-term contract). He joined the B3OA Lab on 03/01/2022. He will provide technical support to our IMOSAR imaging platform. See his profile.

Our latest publications

Experimental Type 2 Diabetes Differently Impacts on the Select Functions of Bone Marrow-Derived Multipotent Stromal Cells

These results provided evidence that the type 2 diabetes environment impairs multipotent stromal cell expansion and select functions pertinent to their efficacy when used in autologous cell therapies.

Human dentin characteristics of patients with osteogenesis imperfecta: insights into collagen-based biomaterials

We investigated the collagen, mineral and mechanical properties of dentin from deciduous teeth collected from patients with mild form of osteogenesis imperfecta and displaying no obvious clinical signs of dentinogenesis imperfecta. For the first time, an increase in the hardness of osteogenesis imperfecta dentin associated with an increase in mineral content compared to healthy patients was reported.

Does physical exercise always improve bone quality in rats?

This literature review presents for the first time the effects on five exercise models (treadmill running, wheel running, swimming, resistance training and vibration modes) in three different experimental rat groups (males, females, osteopenic) on bone quality.

Does eccentric-concentric resistance training improve early functional outcomes compared to concentric resistance training after total knee arthroplasty?

This study showed that early combined eccentric-concentric rehabilitation after total knee arthroplasty appears to be associated with improved outcomes compared to classic concentric rehabilitation protocols, on both physical function and quality of life.

Osteogenic-differentiated mesenchymal stem cell-secreted extracellular matrix as a bone morphogenetic protein-2 delivery system for ectopic bone formation

This study provided evidence that the osteoinductive potential of BMP-2 was greater when loaded within an osteogenic MSC-derived ECM.