The laboratory of Osteoarticular Biology, Bioengineering and Bioimaging  (B3OA) UMR CNRS 7052 INSERM U1271 is affiliated with the CNRS Ingénierie , with the INSERM , with the Paris Cité University  and with the Ecole Nationale Vétérinaire de Maisons-Alfort . Since its creation in 1977, the laboratory has developed a renowned  expertise in repair and imaging of skeletal tissues. Based on its experience, the B3OA’s mission is to deliver world-class research and education on osteo-articular bioengineering and imaging.

Vue du laboratoire

Our history

L. Sedel, Professor of Orthopaedic Surgery, founded the Laboratory of Orthopaedic Research (LOR) in 1977. This laboratory, a department of the University Paris Diderot, was affiliated with the CNRS Department of Science for Engineers (SPI), and addressed several scientific issues pertaining to orthopaedic surgery. LOR was the first unit of CNRS dedicated to orthopaedic surgery, which focused on various aspects of basic bone biomechanics and on improving the success of implanted hip prostheses. Implementation of a dynamic recruitment policy brought to LOR qualified researchers who expanded the repertory of research at LOR to the field of bone regenerative medicine at the cellular, molecular and genetic levels.

In 1998, the LOR merged with the Laboratory of Experimental Radiology (LER) with expertise in imaging bone in health and disease. Prof. J.D. Laredo, Head of the Department of Radiology at the Lariboisière Hospital, was also in charge of LER. In order to enhance its osteo-articular identity and strengthen its competiveness, the unit was reorganized in 2008  and adopted the new name Laboratory of Osteoarticular Bioengineering and Bioimaging (B2OA).

In 2019, the laboratory was renewed with H. Petite as Director and R. Nizard as Deputy Director under the name of Laboratoire de Biologie, Bioingéniérie et Bioimagerie ostéoarticulaire (B3OA).

Since its foundation, the laboratory has been located at the Villemin campus of University Paris Cité medical school in Paris 10th district.

Our research activities

Its expert knowledge and skills in tissue engineering, imaging, and cellular and molecular biology allow the laboratory to develop new and innovative translational approaches for orthopedic, odontology and radiology medical fields.

Our other activities

Beside its research endeavor, the B3OA also aims at using its expertise to provide top-class:

  • Teaching for third cycle students;
  • Traning for master and PhD candidates;
  • Education for surgeons and clinicians to bring acquired knowledge to the patient’s bed-side in order to improve actual treatments and diagnosis.

Our members

The B3OA Lab research team is composed of biologists, dentists, veterinarians, orthopaedic surgeons, and radiologists. It includes about 35 permanent and 10 temporary staff members (see here the organization of B3OA).

Our tutoral authorities