Principal investigators: V. Bousson, J.D. Laredo

Investigators: S. Pallu

An important parameter of cortical bone strength is its microstructure. We study the microstructure of cortical bone with 3D high resolution imaging (synchrotron radiation), its evolution with aging and its link with the osteoporotic fracture of the proximal femur.

Microradiographie d’une section d’os cortical de la mi-diaphyse du fémur montrant différents niveaux de gris des lamelles des ostéons ce qui traduit différents degrés de minéralisation

The level of mineralization of bone tissue is also a qualitative parameter that intervenes in its mechanical strength. We study its variation in function of gender, age and its relationship to osteoporotic fracture of the proximal femur.