Here, we provide a comprehensive review of plausible metabolic switches in response to
implantation and of the various strategies currently used to leverage MSC metabolism
to improve stem cell-based therapeutics.
Rebecca is a PhD candidate. She will work on the impact of oxidative stress induced by the diabetic microenvironment on bone repair and on the therapeutic potential of mesenchymal stem cells associated with cyclodextrin-astaxanthin antioxidant complexes She joined our laboratory… Read More
Pauline is a PhD candidate. She will work on the development of a composite biomaterial able to increase the survival and functionality of Mesenchymal Stem Cells transplanted into a large bone defect. She joined our laboratory on October 3, 2019.She… Read More
PhD defended by Cyprien DENOEUD on 30-09-2019
The documentary recounts the 5 original encounters between Villejuif residents, which took place in spring 2019 at the Elsa-Triolet Media Library in Villejuif, as part of the 80th CNRS anniversary celebrations. This is the opportunity to explore from an original… Read More
Our results showed that the addition of only low dose of BMP-2 was beneficial to enhance the bone-forming potential of MSCs, whereas high dose of BMP-2 overcame the advantage of combining this growth factor with MSCs.
Fractures: the amazing healing ability of our bones!
Defended by Karim OUDINA on 09-2015
Repairing bones with stem cells The use of stem cells for bone repair becomes possible thanks to a nutritive hydrogel developed by researchers from the Laboratory of Osteoarticular Bioengineering and Bioimaging, in collaboration with members of the Ermecee. This hydrogel… Read More
Cryopreserved and then grafted, the transformation of the aorta into a trachea. For a long time difficult, the trachea and bronchi have only had a reliable transplant protocol for a few years. The operation, conducted by doctors from the Paris… Read More
Dr. Adrien Moya has just started a post-doc at the University of Miami in the lab of Paul Schiller. Here we discuss Dr. Moya’s previous work in the CNRS lab at Diderot University in Paris. His recent publication in Stem Cells … Read More
In this uncontrolled study, airway bioengineering using stented aortic matrices demonstrated feasibility for complex tracheal and bronchial reconstruction.
In certain bone pathologies or fractures, the repair strategy of reference is to graft a piece of bone of the patient in th defect to repair. With stem cells seeded onto coral skeleton, one could improve bone repair. For now,… Read More
The medical imaging techniques currently developed make it possible to obtain more and more powerful images. This film presents the work of 4 laboratories specialized in the observation of the bone. A CNRS Image movie. Report from October 2011. Find… Read More
At the Lariboisière Hospital (Paris), research on biomaterials allowed, after implantation of coral seeded with stem cells in sheeps, a good repair of bone defect. While waiting for the applications on the man … An episode of the series “Des… Read More
What are the bones used for? How do our joints handle shocks? What happens when you have a sprain or dislocation? How is the skeleton formed during fetal life? And during growth, how do the bones lengthen? What is scoliosis?… Read More
Artificial retina, glasses equipped with cameras? Technology to help the visually impaired? Synthetic blood: soon a reality? To meet the needs of the sick and wounded, the researchers managed to make “blood”? Artificial skin created in the laboratory? E =… Read More
The invention relates to a method for controlling the mechanical strength of a part inserted at least partially in a body.
The invention relates to an implant device and a delivery tool.
The invention relates to a method for culturing bone tissue.
The present invention relates generally to a hydrogel releasing glucose in a time-controlled manner, to medical applications thereof, and to a method for preparing said hydrogel.
The present study provided evidence that T2DM impairs bone formation in critical-size calvarial defects and markedly reduces angiogenesis in all defects regardless of the defect size tested.
Defended by Adrien MOYA on 14-09-2016
Defended by Jonathan RIBOT on 15-12-2015